Fatty alcohol esters
Medchemexpress LLC Linaclotide acetate | 851199-60-5 | 98.6% | 1586.79 | C61H83N15O23S6 | 10 MG
Linaclotide acetate is a potent, selective guanylate cyclase C (GC-C) agonist developed for treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation. Supplied as a research-grade peptide, it acts on intestinal GC-C receptors to increase chloride and bicarbonate secretion and accelerate intestinal transit, supporting pharmacological and translational studies under appropriate laboratory conditions.
- Potent, selective guanylate cyclase C agonist
- Promotes chloride and bicarbonate secretion to increase intestinal fluid
- Peptide suitable for research-grade in vitro and in vivo studies
- High purity and characterized molecular weight for reproducible results
- Stable when stored frozen; follow recommended storage conditions
Medchemexpress LLC L-Arginyl-L-lysyl-L-histidine compound with acetic acid (1:x) | 99.5% | 439.51 (free acid) | 10 MG
RKH acetate is a peptide, chemically known as L-Arginyl-L-lysyl-L-histidine compound with acetic acid. It exhibits protective effects against sepsis-induced death and organ damage by directly binding to Toll-like receptor 4 (TLR4) and blocking its signal transduction within immune cells.
- Exerts protective effects against sepsis-induced death and organ damage.
- Directly binds to Toll-like receptor 4 (TLR4).
- Blocks TLR4 signal transduction in immune cells.
- Target: Toll-like receptor (TLR).
- Pathway: Immunology/inflammation.
- Molecular formula: C18H33N9O4.xC2H4O2.
Medchemexpress LLC PNC-27 acetate | 99.9% | 4031.73 | 50 MG
PNC-27 acetate is a chimeric p53-penetratin peptide that binds to HDM-2 in a p53 peptide-like structure. It induces selective membrane-pore formation and leads to cancer cell lysis. PNC-27 acetate is an anticancer peptide and can be used in acute myeloid leukemia research.
- Induces cancer cell death.
- Binds to cell membrane-bound HDM-2 in A2058 and MCF-7 cells.
- Shows anti-leukemia activity in mice.
- Reduces AML engraftment and prolongs survival in AML mice.
Cayman Chemical Farnsyl Alcohol 25mg
An isoprenoid with diverse biological activities; an agonist of PPARα and PPARγ (EC50s = 5.5 and 28 µM, respectively, in a reporter assay using CV-1 cells); increases the expression of mRNA encoding the PPARα targets CPT1 and ACS at 100 µM; a fungal quorum-sensing molecule; inhibits the yeast-to-mycelium conversion in C. albicans at 250 µM; decreases the severity of oral candidiasis induced by C. albicans, but does not reduce C. albicans viability or the number of CFUs, in prednisolone-immunosuppressed mice at 1.125, 2.25, and 9 µmol/animal; repels S. medanensis mites at 0.02-0.1 mg/cm2 and is toxic to those same mites in a contact assay (LC50 = 0.048 mg/cm2 per vial)
Cayman Chemical DL-Tryptophn octyl esterhy 1g
A stable, cell-permeable tryptophan derivative with an octyl ester protected COOH group
Sigma Aldrich Fine Chemicals Biosciences Octyl beta D glucopyranosi100G
Octyl beta D glucopyranosi100G
Medchemexpress LLC Thymopentin acetate | 89318-88-7 | 1 ML
Thymopentin acetate is a biologically active peptide secreted mainly by the epithelial cells of the thymic cortex and medulla. It serves as an effective immunomodulatory agent.
- Short plasma half-life of 30 seconds.
- Enhances the generation of T-cell lineage derived from human embryonic stem cells (hESCs).
Medchemexpress LLC Abiraterone acetate | 154229-18-2 | MFCD00934213 | 99.9% | 10 MG
Abiraterone acetate analytical standard is the acetate ester prodrug of abiraterone, used as a reference compound in research and analytical assays targeting CYP17A1 activity. It is provided as a highly pure material suitable for identity confirmation, method development, and quantitative analysis.
- intended for research and analytical applications.
- validated identity with CAS 154229-18-2.
- molecular formula C26H33NO2 and molecular weight 391.55.
- high purity suitable for use as a reference standard.
- compatible with chromatography and assay development workflows.
Apexbio Technology LLC Pasireotide Acetate 396091-76-2 10mg
Pasireotide Acetate (CAS 396091-76-2) is a cyclohexapeptide somatostatin analog that acts as a multi-receptor ligand selectively activating several somatostatin receptor subtypes (sst1/2/3/5 with pKi values of 8 2 9 0 9 1 and 9 9 respectively) By modulating these receptors Pasireotide Acetate regulates the secretion of growth hormone insulin-like growth factor I (IGF-I) and adrenocorticotropic hormone (ACTH) at the cellular level Preclinical investigations indicate its capacity to alter endocrine hormone release with implications for studies in acromegaly and Cushing s disease Its demonstrated effects on secretion inhibition proliferation control and induction of apoptosis make it a valuable tool in studies of related biological pathways
Apexbio Technology LLC nor-NOHA (acetate) 1140844-63-8 10mg
nor-NOHA (acetate) (CAS 1140844-63-8) is a potent reversible inhibitor of rat liver arginase (Ki 0 5 M) By competitively inhibiting arginase nor-NOHA modulates the cellular balance between the L-arginine-dependent pathways of nitric oxide synthase (NOS) and arginase affecting nitric oxide production and urea cycle metabolism In vitro studies have shown that nor-NOHA suppresses proliferation migration and invasion of HepG2 hepatocellular carcinoma cells induces apoptosis and alters expression of Arg1 MMP-2 P53 and ECD In vivo nor-NOHA improves endothelial function in rat models of inflammation by enhancing NOS activity increasing EDHF and reducing superoxide anion production This compound is widely used to investigate arginase-related mechanisms in cellular and vascular biology
Medchemexpress LLC ATIC-IN-1 acetate | 3067165-96-9 | C23H37N7O7 | 50 MG
ATIC-IN-1 acetate is an inhibitor that targets Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) dimerization with a Ki value of 685 nM. ATIC catalyzes de novo purine biosynthesis, and its dimerization is crucial for AICAR transformylase activity. This inhibitor demonstrates anti-tumor activity by reducing cell numbers and cell division rates and inhibits the proliferation of MCF-7 cells.
- Targets ATIC dimerization with a Ki value of 685 nM
- Inhibits proliferation of MCF-7 cells
- Reduces cell numbers and cell division rates
- Suitable for studying respiratory diseases, cancer, pulmonary disease, and lung fibrosis
Medchemexpress LLC Flecainide (acetate) | 54143-56-5 | 99.4% | 474.39 | 50 MG
Flecainide acetate (R-818) is a class 1C antiarrhythmic agent primarily used for the management of supraventricular arrhythmia. It functions by blocking the Nav1.5 sodium channel in the heart, leading to the prolongation of the cardiac action potential.
- Class 1C antiarrhythmic agent
- Blocks the Nav1.5 sodium channel
- Causes prolongation of the cardiac action potential
- For research use only
Medchemexpress LLC Cetrorelix Acetate | 145672-81-7 | 99.92% | 1491.09 | 10 MG
Cetrorelix Acetate, also known as SB-75 acetate, is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM. It is intended for research use only.
- Inhibits the growth of ES-2 cell line at 1000 ng/mL
- Shows comparable antiproliferative effects to GnRH-I agonists
- Utilized in research for conditions such as Polycystic Ovarian Syndrome and Infertility
Medchemexpress LLC PNC-28 acetate | 392661-17-5 | 98.8% | 3509.13 (free acid) | 10 MG
PNC-28 acetate is a peptide derived from the mdm-2-binding domain (residues 17-26) of the p53 protein, incorporating a membrane-crossing-penetratin sequence. This compound is suitable for use in pancreatic cancer research.
- Can be used for pancreatic cancer research
- Blocks growth of a lethal human pancreatic cancer cell line in vitro
- Inhibits BMRPA1. Tuc3 tumor growth in vivo, particularly when delivered directly to the tumor
Medchemexpress LLC L-(-)-Bornyl acetate | 5655-61-8 | 196.29 | 1 ML
L-(-)-Bornyl acetate is supplied as a liquid, primarily used as a laboratory chemical and for the manufacture of substances. This compound is stable under recommended storage conditions.
- Appearance as a colorless to light yellow liquid.
- Stable under recommended storage conditions.
- Container should be kept tightly sealed in a cool, well-ventilated area.
- Keep away from direct sunlight and sources of ignition.
- Recommended storage for pure form is -20°C for 3 years or 4°C for 2 years.
- Recommended storage in solvent is -80°C for 6 months or -20°C for 1 month.
- Shipping at room temperature if less than 2 weeks.